Biologically Derived Metal-Organic Framework Used for DNA Simulation

Chemical engineers from Ecole Polytechnique Fédérale de Lausanne (EPFL) developed biologically derived “metal-organic framework” (bio-MOFs) that mimics what occurs on DNA double helix.
April 12, 2019

Researchers from Switzerland used a biologically derived MOF as a “nanoreactor”.

Категория: biotech

Biologically Derived Metal-Organic Framework Used for DNA Simulation

Swiss scientists have synthesized a biologically derived replica of DNA. Chemical engineers from Ecole Polytechnique Fédérale de Lausanne (EPFL) developed biologically derived “metal-organic framework” (bio-MOFs) that mimics what occurs on DNA double helix.

MOFs have been traditionally used in chemical catalysis. Researchers from Switzerland led by Kyriakos Stylianou used a biologically derived MOF as a “nanoreactor” for studying adenine molecules – tiny otherwise-inaccessible complex biomolecules, one of the four nucleobases in the nucleatic acid of DNA.

“…our study highlights the utility of biologically derived MOFs as nanoreactors for capturing biological molecules through specific interactions, and for transforming them into other molecules," says Stylianou.